SARS-COV-2 related products

Introduction

Based on over 10 years biotechnology research experience, Beacle developed SARS-COV-2 related products.
SARS-COV-2 is a virus having  an envelope structure. Several proteins including Spike (S) proteins are displayed on the envelope, and in the envelope  nucleus (N) protein make a complex with its RNA gene.   The infection is revealed to start form the binding of S protein’s SB domain to ACE2 receptors of host cells and subsequent viral enters into host cells through endocytosis.   Viral RNA is then released into cells by the aid of S protein’s S2 domain through  membrane fusion system. N protein is the most abundant protein of SARS-COV-2 and highly immunogenic,  and infected human often shows high antibody to N proteins. N protein is composed of three domains, called N terminus domain (NTD) related with RNA binding, C terminus domain (CTD) related with formation of complexes, and liner region of the two domains which is related with phosphorylation.  Many vaccines are developed against SARS-COV-2 infection, and all of them utilizes S protein as the target molecule.

Product outline

1. SARS-COV-2 antigens.  

1) N proteins
 NTD: N terminus domain of N protein produced in E. coli. Two types of proteins (thioredoxin-his tag and non-tag) are available.
 CTD: C terminus domain of N protein produced in E. coli. Two types of proteins (thioredoxin-his tag and non-tag) are available.
 full length N proteins: full length N protein produced in E. coli. Two types of proteins (thioredoxin-his tag and non-tag) are available.
For detail see datasheet

2. Anti-SARS-COV-2 antibody quantitative ELISA kit

1) Anti-N protein antibody ELISA kit
Antibodies that binds to full length N proteins are quantitatively measured by the kit using attached standard antibody. The kit utilizes our original antibody detection probe and highly sensitive.
For detail see datasheet(in preparation)

Product lineup

product #product nameContentPrice
BCL‐CON-N01SARS-COV-2 NTD-tag100μg60000円
BCL‐CON-N02SARS-COV-2 NTD100μg65000円
BCL‐CON-C01SARS-COV-2 CTD-tag100μg60000円
BCL‐CON-C02SARS-COV-2 CTD100μg65000円
BCL‐CON-F01SARS-COV-2 Full length-tag100μg80000円
BCL‐CON-F02SARS-COV-2 Full length100μg85000円
BCL‐COK-NA01Anti-N protein antibody quantitative ELISA kit96 assayavailable soon

Q&A

in preparation

Manual and MSDS

 in preparation.